Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920408 | 0.74 | CHEK1 (0.36) | MEN1ALDH1A1KMT2AHDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL7208149 | 0.72 | CHEK1 (0.36) | MEN1ALDH1A1KMT2AHDAC4HDAC7 | |
| SCHEMBL7479940 | 0.70 | SCN9A (0.40) | SCN9AMEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL10471795 | 0.63 | — | — | |
| SCHEMBL5423024 | 0.63 | CES1 (0.67) | CDC25AALDH1A1 | |
| SCHEMBL7479946 | 0.63 | SCN9A (0.40) | SCN9AGRM2MEN1KMT2AHDAC3 | |
| SCHEMBL7832520 | 0.61 | MEN1 (0.44) | MEN1ALDH1A1KMT2AHDAC4HDAC7 | |
| SCHEMBL11750297 | 0.61 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL5222768 | 0.60 | OPRK1 (0.39) | — | |
| SCHEMBL7858451 | 0.59 | HDAC3 (0.63) | MEN1ALDH1A1KMT2AHSD17B10HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089981-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS. | Elan Pharmaceuticals, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067220-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |