Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3644097 | 0.85 | NOTUM (0.51) | HRH3 | |
| SCHEMBL1353798 | 0.85 | GFER (0.43) | — | |
| SCHEMBL15990720 | 0.81 | CA12 (0.43) | F10 | |
| SCHEMBL3440218 | 0.77 | CYP2C9 (0.45) | ITGB3ITGA2BLSSHRH3F10 | |
| SCHEMBL1018020 | 0.77 | ROCK2 (0.37) | — | |
| SCHEMBL28179053 | 0.76 | CHKA (0.48) | ITGB3ITGA2BHRH3F10TSHR | |
| SCHEMBL9462210 | 0.76 | RBP4 (0.43) | HRH3 | |
| SCHEMBL785159 | 0.75 | F10 (0.51) | ITGB3ITGA2BLSSHRH3F10 | |
| SCHEMBL2942824 | 0.75 | ITGB3 (0.63) | ITGB3ITGA2BLSSCHKA | |
| SCHEMBL7334686 | 0.74 | MAPT (0.54) | ITGB3ITGA2BLSSHRH3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | ITGB3 2555/4885ITGA2B 1864/4885LSS 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.