Phenol

Phenol

SCHEMBL7858678

CC(C)(C)c1cc(O)cc(C(C)(C)C)c1.Oc1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.73
GABRB2 P47870 1/20 0.73
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52
ESR1 P03372 5/20 0.50
ESR2 Q92731 5/20 0.50
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
GLA P06280 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
EGFR P00533 1/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28225678 0.88 GABRA1 (0.56) GABRA1GABRB2LMNATYRESR1
Phenol SCHEMBL28079008 0.87 GABRA1 (0.54) GABRA1GABRB2LMNATYRESR1
Phenol SCHEMBL27853938 0.86 ESR1 (0.57) GABRA1GABRB2LMNATYRESR1
Phenol SCHEMBL28112897 0.85 GABRA1 (0.52) GABRA1GABRB2LMNATYRESR1
SCHEMBL18268 0.85 GABRA1 (1.00) GABRA1GABRB2LMNATYRESR1
Phenol SCHEMBL7192832 0.84 ALDH1A1 (0.54) GABRA1GABRB2LMNATYRESR1
Tert-Butylbenzene SCHEMBL27837703 0.84 LMNA (0.61) GABRA1GABRB2LMNATYRESR1
Phenol SCHEMBL28257274 0.83 LMNA (0.75) GABRA1GABRB2LMNATYRESR1
Tert-Butylbenzene SCHEMBL27389999 0.83 LMNA (0.67) GABRA1GABRB2LMNATYRESR1
SCHEMBL14973413 0.83 GABRA1 (0.94) GABRA1GABRB2LMNATYRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101658470-B Moisturizer and preparation method thereof BEIJING OKEANOS TECH CO., LTD. (CN) 2012-02-22 CN disclosed
CN-101658470-A Moisturizer and preparation method thereof OKEANOS TECH CO LTD 2010-03-03 CN disclosed
JP-2001089406-A METHOD OF PRODUCING p,p'-BIPHENOL SUMITOMO CHEM CO LTD 2001-04-03 JP disclosed