Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 5/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755080 | 0.85 | CSNK2A1 (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL26800 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10865352 | 0.70 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL322274 | 0.69 | PKM (0.52) | CHUKKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29803190 | 0.69 | PKM (0.52) | CHUKKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL551783 | 0.69 | SMN1; SMN2 (0.54) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL552239 | 0.69 | CSNK2A1 (0.67) | CHUKKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1163541 | 0.68 | CA12 (0.64) | CHUKKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10781901 | 0.68 | CA12 (0.64) | CHUKKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL894682 | 0.66 | KDM4E (0.69) | CHUKKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741734-B1 | PHENYLBORONIC ACID COMPLEXES | PROLINX INC (US) | 2001-04-04 | — | — | EP | disclosed |
| US-6008406-A | Phenylboronic acid complexing reagents derived from aminosalicylic acid | PROLINX, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| US-5688928-A | Phenylboronic acid complexing reagents derived from aminosalicylic acid | PROLINX, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| US-5668258-A | Phenylboronic acid complexing reagents derived from aminosalicylcic acid | PROLINX, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| US-5668257-A | Phenylboronic acid complexing reagents derived from aminolalicylic acid | PROLINX, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| US-5648470-A | Phenylboronic acid complexing reagents derived from aminosalicyclic acid | PROLINX, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| US-5594151-A | Phenylboronic acid complexing reagents derived from aminosalicylic acid | PROLINX, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0741734-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020591-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1995-08-03 | — | — | WO | disclosed |