Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754485 | 0.84 | DYRK1A (0.46) | S1PR1S1PR3ASIC3PIK3CDCD274 | |
| Hydrochloric Acid SCHEMBL859783 | 0.78 | TGFBR1 (0.42) | S1PR1S1PR3ASIC3CD274DYRK1A | |
| SCHEMBL12998010 | 0.77 | PIK3CA (0.54) | S1PR1S1PR3ASIC3PIK3CDCYP2A6 | |
| SCHEMBL3797512 | 0.77 | S1PR1 (0.45) | S1PR1S1PR3ASIC3CD274DYRK1A | |
| SCHEMBL2724081 | 0.77 | ASIC3 (0.37) | S1PR1S1PR3ASIC3PIK3CDCD274 | |
| SCHEMBL3793368 | 0.76 | HCAR3 (0.39) | S1PR1S1PR3ASIC3DYRK1AMAPT | |
| Hydrochloric Acid SCHEMBL3281306 | 0.76 | CD274 (0.43) | S1PR1S1PR3ASIC3CD274DYRK1A | |
| SCHEMBL20565297 | 0.75 | PNMT (0.53) | S1PR1S1PR3ACHE | |
| SCHEMBL30174754 | 0.75 | PNMT (0.53) | S1PR1S1PR3ACHE | |
| Hydrochloric Acid SCHEMBL9278402 | 0.74 | PIK3CD (0.51) | S1PR1S1PR3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |