Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 8/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LATS1 | O95835 | 2/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 4/20 | 0.32 |
| ▸ | CCND1 | P24385 | 4/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172045 | 0.82 | LMNA (0.36) | GLP1RPOLBLMNASMN1; SMN2CDK2 | |
| SCHEMBL7170682 | 0.82 | GLP1R (0.39) | GLP1RPOLBAPEX1LMNASMN1; SMN2 | |
| SCHEMBL21032606 | 0.79 | PGK1 (0.34) | POLBAPEX1CYP1A2CYP2C19 | |
| SCHEMBL31470280 | 0.75 | ALDH1A1 (0.30) | RAB9A | |
| SCHEMBL21011971 | 0.75 | ALDH1A1 (0.30) | RAB9A | |
| SCHEMBL7172248 | 0.72 | HDAC4 (0.45) | POLBLMNASMN1; SMN2CDK2CCNE2 | |
| SCHEMBL2914288 | 0.72 | CDK2 (0.35) | GLP1RPOLBLMNASMN1; SMN2CDK2 | |
| SCHEMBL7857463 | 0.71 | KHK (0.53) | GLP1RSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7177583 | 0.70 | ALDH1A1 (0.50) | GLP1RPOLBLMNASMN1; SMN2SCN9A | |
| SCHEMBL7858360 | 0.70 | POLB (0.36) | GLP1RPOLBAPEX1SMN1; SMN2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1196683-C | Amino-compound | YUNAGA PHARMACEUTICAL CO LTD (JP) | 2005-04-13 | — | — | CN | disclosed |
| CN-1105715-C | Novel pyridonecarboxylic acid derivative or salt thereof, and antibacterial agent containing same as active ingredient | WAKUNAGA PHARMA CO LTD (JP) | 2003-04-16 | — | — | CN | disclosed |
| EP-0911327-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR THEIR SALTS AND ANTIBACTERIAL AGENT COMPRISING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-6156903-A | Pyridonecarboxylic acid derivatives or their salts, and antibacterial agents containing the same as their effective components | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| US-6133284-A | EXCELLENT BACTERICIDAL PROPERTIES AND ORAL ABSORPTION; INFECTIONS FROM GRAMNEGATIVE AND -POSITIVE BACTERIA; INTESTINAL ABSORPTION, METABOLIC STABILITY; SIDE EFFECT REDUCTION; NONPHOTOTOXICITY AND NONCYTOTOXICITY | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| CN-1258672-A | Amino-compound | YUNAGA PHARMACEUTICAL CO LTD (JP) | 2000-07-05 | — | — | CN | disclosed |
| CN-1258674-A | Pyrone carboxylic acid derivate or its salt and antibiotic with the same as effective component | YUNAGA PHARMACEUTICAL CO LTD (JP) | 2000-07-05 | — | — | CN | disclosed |
| EP-0992501-A2 | Pyridonecarboxylic acid derivatives as antibacterial agents | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5998436-A | Pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising the same as the active ingredient | WAKUNAGA PHARMACEUTICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0952151-A2 | Intermediates for use in preparing novel pyridonecarboxylic acid derivatives or their salts | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-27 | — | — | EP | disclosed |
| EP-0911327-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR THEIR SALTS AND ANTIBACTERIAL AGENT COMPRISING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-28 | — | — | EP | disclosed |
| CN-1201459-A | Novel pyridonecarboxylic acid derivative or salt thereof, and antibacterial agent containing same as active ingredient | WAKUNAGA PHARMA CO LTD (JP) | 1998-12-09 | — | — | CN | disclosed |