Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860431 | 0.89 | XDH (0.54) | ALDH1A1RAB9ATSHRSMN1; SMN2HTT | |
| SCHEMBL5404259 | 0.88 | XDH (0.63) | XDH | |
| SCHEMBL7865070 | 0.87 | ALDH1A1 (0.61) | ALDH1A1RAB9ATSHRSMN1; SMN2HTT | |
| SCHEMBL7861879 | 0.87 | ALDH1A1 (0.56) | ALDH1A1RAB9ATSHRSMN1; SMN2HTT | |
| SCHEMBL7861685 | 0.79 | XDH (0.78) | XDH | |
| SCHEMBL5419342 | 0.79 | XDH (0.63) | XDH | |
| SCHEMBL31117196 | 0.76 | HTT (0.72) | ALDH1A1RAB9ATSHRSMN1; SMN2HTT | |
| SCHEMBL4161763 | 0.76 | HTT (0.72) | ALDH1A1RAB9ATSHRSMN1; SMN2HTT | |
| SCHEMBL28986730 | 0.76 | NOTUM (0.56) | XDH | |
| SCHEMBL7861833 | 0.76 | XDH (0.46) | ALDH1A1HTTXDHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936217-B1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | WELFIDE CORP (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6015829-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0936217-A1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |