Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860451 | 0.89 | ALDH1A1 (0.56) | XDHHTTALDH1A1KDM4ERAB9A | |
| SCHEMBL5419342 | 0.88 | XDH (0.63) | XDH | |
| SCHEMBL7861833 | 0.87 | XDH (0.46) | XDHHTTALDH1A1KDM4E | |
| SCHEMBL7861685 | 0.79 | XDH (0.78) | XDH | |
| SCHEMBL5404259 | 0.79 | XDH (0.63) | XDH | |
| SCHEMBL6052323 | 0.77 | XDH (0.47) | XDH | |
| SCHEMBL28986730 | 0.76 | NOTUM (0.56) | XDH | |
| SCHEMBL7861879 | 0.76 | ALDH1A1 (0.56) | XDHHTTALDH1A1KDM4ERAB9A | |
| SCHEMBL7865070 | 0.75 | ALDH1A1 (0.61) | HTTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7865140 | 0.75 | XDH (0.54) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936217-B1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | WELFIDE CORP (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6015829-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0936217-A1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |