Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | BLVRB | P30043 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861879 | 0.89 | ALDH1A1 (0.56) | XDHHTTKDM4EALDH1A1 | |
| SCHEMBL7865140 | 0.88 | XDH (0.54) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL7860431 | 0.87 | XDH (0.54) | XDHHTTKDM4EALDH1A1 | |
| SCHEMBL5415067 | 0.79 | XDH (0.58) | XDH | |
| SCHEMBL5407349 | 0.79 | XDH (0.54) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL28986731 | 0.76 | NOTUM (0.56) | XDH | |
| SCHEMBL7860451 | 0.76 | ALDH1A1 (0.56) | XDHHTTKDM4EALDH1A1 | |
| SCHEMBL7865070 | 0.75 | ALDH1A1 (0.61) | HTTKDM4EALDH1A1 | |
| SCHEMBL4718687 | 0.75 | XDH (0.56) | XDHSLC22A12ALDH1A1ABCC4ABCB11 | |
| SCHEMBL5419342 | 0.75 | XDH (0.63) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936217-B1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | WELFIDE CORP (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6015829-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0936217-A1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |