Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 8/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.40 |
| ▸ | PPIF | P30405 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861123 | 0.96 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CNISCHCYP19A1 | |
| SCHEMBL7861066 | 0.90 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CNISCHCYP19A1 | |
| SCHEMBL7864328 | 0.86 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CNISCHCYP19A1 | |
| SCHEMBL7861000 | 0.86 | ADRA2B (0.47) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL7860109 | 0.82 | ADRA2B (0.47) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL7861283 | 0.81 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CNISCHCYP19A1 | |
| SCHEMBL7861142 | 0.81 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CNISCHCYP19A1 | |
| SCHEMBL7862258 | 0.75 | ADRA2B (0.50) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL9440611 | 0.74 | NISCH (0.50) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL7859939 | 0.72 | ADRA2B (0.64) | ADRA2AADRA2BADRA2CNISCHMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | claimed |
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |