Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.47 |
| ▸ | MAOA | P21397 | 10/20 | 0.47 |
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854564 | 1.00 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL3169171 | 0.91 | NISCH (0.52) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL9197682 | 0.89 | ADRA2B (0.61) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL9206145 | 0.89 | ADRA2B (0.60) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL7860101 | 0.87 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL7854333 | 0.87 | ADRA2B (0.46) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL7859921 | 0.87 | ADRA2B (0.46) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL9199669 | 0.85 | ADRA2B (0.64) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL9201690 | 0.83 | ADRA2B (0.67) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL7861283 | 0.83 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |