Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 14/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.67 |
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.54 |
| ▸ | MAOA | P21397 | 8/20 | 0.54 |
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207151 | 0.92 | ADRA2B (0.63) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL9197682 | 0.90 | ADRA2B (0.61) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL9201353 | 0.89 | ADRA2A (0.66) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL3169171 | 0.89 | NISCH (0.52) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL9640404 | 0.88 | ADRA2B (0.65) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL9199669 | 0.88 | ADRA2B (0.64) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL7854312 | 0.87 | ADRA2B (0.50) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL7854252 | 0.84 | MAOA (0.59) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL7861399 | 0.83 | ADRA2A (0.47) | ADRA2BADRA2CADRA2ANISCHMAOA | |
| SCHEMBL7854564 | 0.83 | ADRA2A (0.47) | ADRA2BADRA2CADRA2ANISCHMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3135960-A | — | — | None | — | — | JP | disclosed |
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| JP-H03135960-A | PHENOXY-HETEROCYCLIC COMPOUNDS | MERRELL DOW PHARMACEUT INC | 1991-06-10 | — | — | JP | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |