Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211366 | 0.91 | ELANE (0.49) | ELANETDP1ATML3MBTL1HPGD | |
| Acrylic Acid SCHEMBL28239256 | 0.83 | THRB (0.43) | THRBTGM2AKT1TDP1ATM | |
| Acrylic Acid SCHEMBL28161077 | 0.82 | ELANE (0.63) | ELANETHRBTGM2AKT1TDP1 | |
| SCHEMBL11426974 | 0.79 | ELANE (0.46) | ELANETHRBTGM2AKT1TDP1 | |
| Acrylic Acid SCHEMBL3913076 | 0.79 | THRB (0.55) | THRBTGM2AKT1TDP1ATM | |
| Acrylic Acid SCHEMBL6692818 | 0.79 | THRB (0.46) | THRBTGM2AKT1TDP1ATM | |
| Acrylic Acid SCHEMBL6692820 | 0.79 | THRB (0.46) | ELANETHRBTGM2AKT1TDP1 | |
| SCHEMBL8238681 | 0.76 | ELANE (0.44) | ELANETHRBTGM2AKT1TDP1 | |
| Acrylic Acid SCHEMBL27653442 | 0.76 | AKT1 (0.50) | THRBTGM2AKT1TDP1ATM | |
| Acrylic Acid SCHEMBL28261897 | 0.76 | ALDH1A1 (0.41) | ELANETHRBTGM2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124786-A1 | PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA-METHYLENE- BETA-HYDROXY ACIDS | Uniroyal Chemical Company, Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000027793-A1 | PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA- METHYLENE- BETA- HYDROXY ACIDS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-05-18 | — | — | WO | disclosed |