Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | TKT | P29401 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591752 | 0.79 | KDM1A (0.44) | KDM1AMAOAMAOBHTR1AADRA2A | |
| SCHEMBL27857868 | 0.72 | RAB9A (0.43) | KDM1AMAOAMAOBGRM4 | |
| SCHEMBL18228047 | 0.71 | JAK2 (0.46) | — | |
| SCHEMBL14698505 | 0.69 | GBA1 (0.46) | KDM1AMAOAMAOBHTR1AADRA2A | |
| SCHEMBL12466143 | 0.69 | KDM1A (0.40) | KDM1AMAOAMAOBGRM4 | |
| SCHEMBL7861459 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL2866159 | 0.66 | KDM1A (0.58) | KDM1AMAOAMAOBKCNH2 | |
| SCHEMBL18228507 | 0.65 | GPR119 (0.53) | — | |
| Hydrochloric Acid SCHEMBL29086107 | 0.65 | KDM1A (0.40) | KDM1AMAOAMAOBTKT | |
| SCHEMBL30154778 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683792-B1 | LHRH ANTAGONISTS HAVING MODIFIED AMINOACYL RESIDUES AT POSTIONS 5 AND 6 | ABBOTT LAB (US) | 2001-09-26 | — | — | EP | disclosed |