Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861529 | 0.85 | CTSK (0.40) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL3306254 | 0.83 | AAK1 (0.41) | AAK1CA1CA2CA7CTSK | |
| SCHEMBL7853765 | 0.83 | CTSK (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL7853722 | 0.82 | CA2 (0.45) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL7859375 | 0.82 | CA2 (0.45) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL19227630 | 0.81 | CA1 (0.58) | AAK1CA1CA2CA7CTSK | |
| SCHEMBL7860556 | 0.81 | CTSK (0.47) | CTSKCTSS | |
| SCHEMBL14923598 | 0.80 | AAK1 (0.53) | AAK1CA1CA2CA7CTSK | |
| SCHEMBL14175255 | 0.80 | AAK1 (0.53) | AAK1CA1CA2CA7CTSK | |
| SCHEMBL3375872 | 0.80 | AAK1 (0.53) | AAK1CA1CA2CA7CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5925658-A | PREVENTING OR TREATING ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5891898-A | ANTIULCER AGENT | SANKYO COMPANY, LIMITED (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | disclosed |