Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ENO1 | P06733 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 3/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187314 | 0.81 | ELANE (0.41) | ALDH1A1MBOAT4 | |
| SCHEMBL7862000 | 0.79 | FDPS (0.48) | TSHRFDPSMEN1KMT2A | |
| SCHEMBL9189677 | 0.78 | LMNA (0.44) | ALDH1A1ENO1MEN1KMT2A | |
| SCHEMBL9189651 | 0.77 | HTT (0.46) | ALDH1A1FOLH1MEN1KMT2A | |
| SCHEMBL9189773 | 0.76 | ELANE (0.43) | MBOAT4 | |
| SCHEMBL9187310 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ENO1PRKCAPRKCDCETP | |
| SCHEMBL9193616 | 0.71 | HTT (0.48) | FOLH1MEN1KMT2A | |
| SCHEMBL9192418 | 0.71 | ALDH1A1 (0.39) | ALDH1A1ENO1BTN3A1FDPS | |
| SCHEMBL2456571 | 0.71 | ALDH1A1 (0.42) | ALDH1A1ENO1BTN3A1FDPS | |
| SCHEMBL9193612 | 0.70 | HTT (0.46) | ALDH1A1FOLH1FDPSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416689-B1 | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO INC (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5227506-A | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO., INC. (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0416689-A2 | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO. INC. (US) | 1991-03-13 | — | — | EP | disclosed |