Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860961 | 0.85 | MMP2 (0.34) | MAPTGAAMMP2MMP9ALDH1A1 | |
| SCHEMBL7861006 | 0.80 | MAPT (0.38) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9206364 | 0.74 | MAPT (0.40) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7864336 | 0.72 | MMP2 (0.31) | MMP2MMP9 | |
| SCHEMBL7861302 | 0.69 | MMP2 (0.35) | MMP2MMP9 | |
| SCHEMBL9208945 | 0.69 | MAPT (0.37) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL7860976 | 0.69 | MAPT (0.33) | MAPTGAAALDH1A1LMNAGUSB | |
| SCHEMBL7854582 | 0.69 | MAPT (0.33) | MAPTGAAALDH1A1LMNAGUSB | |
| SCHEMBL7862018 | 0.69 | ADORA2B (0.33) | — | |
| SCHEMBL7861415 | 0.66 | MMP2 (0.31) | MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | claimed |