Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2466923 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL4631149 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL7893413 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL11529637 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL9344673 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL11587440 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL10355758 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL8663181 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL786259 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL14152424 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735933-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | Gvd Corporation (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4735935-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | Gvd Corporation (US) | 2026-05-06 | — | — | EP | claimed |
| US-12281210-B2 | Treatment process of polymeric dispersions based on the use of specific organic peroxides | ARKEMA FRANCE (FR) | 2025-04-22 | — | — | US | claimed |
| EP-4021949-B1 | TREATMENT PROCESS OF POLYMERIC DISPERSIONS BASED ON THE USE OF SPECIFIC ORGANIC PEROXIDES | ARKEMA FRANCE (FR) | 2025-03-26 | — | — | EP | claimed |
| WO-2025007129-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | GVD CORPORATION (US) | 2025-01-02 | — | — | WO | claimed |
| WO-2025007115-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | GVD CORPORATION (US) | 2025-01-02 | — | — | WO | claimed |
| US-20220298307-A1 | TREATMENT PROCESS OF POLYMERIC DISPERSIONS BASED ON THE USE OF SPECIFIC ORGANIC PEROXIDES | ARKEMA FRANCE (FR) | 2022-09-22 | — | — | US | claimed |
| EP-4021949-A1 | TREATMENT PROCESS OF POLYMERIC DISPERSIONS BASED ON THE USE OF SPECIFIC ORGANIC PEROXIDES | ARKEMA FRANCE (FR) | 2022-07-06 | — | — | EP | claimed |
| EP-3710503-B1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2022-01-05 | — | — | EP | claimed |
| WO-2021037969-A1 | TREATMENT PROCESS OF POLYMERIC DISPERSIONS BASED ON THE USE OF SPECIFIC ORGANIC PEROXIDES | ARKEMA FRANCE (FR) | 2021-03-04 | — | — | WO | claimed |
| EP-1927607-B1 | Two-part polyurethane/vinyl ester hybrid foam system and its use as flame-retardant material and material for pour-and-set foam in openings in buildings | HILTI AG (LI) | 2009-12-23 | — | — | EP | claimed |
| EP-1927609-B1 | Multi-part polyurethane/vinyl ester hybrid foam system and its use | HILTI AG (LI) | 2009-11-04 | — | — | EP | claimed |
| EP-0517290-B1 | Initiator suspensions, their preparation and use | AKZO NOBEL NV (NL) | 1995-06-07 | — | — | EP | claimed |
| US-5362828-A | One of which does not have benzene ring or alkoxy group; emulsion polymerization | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-11-08 | — | — | US | claimed |
| US-4232141-A | ADDING AN AQUEOUS DISPERSION OF POWDERED INITIATOR; EMULSION POLYMERIZATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1980-11-04 | — | — | US | claimed |
| EP-4747309-A1 | POLYMERIC MATERIALS | Colormatrix Holdings, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4743514-A1 | POLYMERIC MATERIALS | Colormatrix Holdings, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| US-4540759-A | Polymerization of vinyl chloride in the presence of a catalyst solubilized prior to exposure to monomer | CHEMISCHE WERKE HUELS AG (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4370276-A | Process for the continuous preparation of dialkylperoxydicarbonates | PEROXIDE CHEMIE GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4232141-A | ADDING AN AQUEOUS DISPERSION OF POWDERED INITIATOR; EMULSION POLYMERIZATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1980-11-04 | — | — | US | disclosed |