Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2466923 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL4631149 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL7893413 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL11529637 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL9344673 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL11587440 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL10355758 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL786724 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL786259 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL14152424 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119427855-A | Laminate and printed circuit board comprising same | 联茂(无锡)电子科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119432039-A | Thermosetting resin composition | 联茂(无锡)电子科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119450924-A | Laminate and method for manufacturing printed circuit board | 联茂(无锡)电子科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118146460-A | Modified ethylene-chlorotrifluoroethylene copolymer, preparation method and application thereof | 浙江省化工研究院有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-116925520-A | BT-like resin composition and prepreg preparation method and application | 南亚新材料科技股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-112638955-B | Propylene copolymer compositions suitable for foaming | 鲁姆斯诺沃伦技术公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116547309-A | Method for producing fluoroelastomers | 索尔维特殊聚合物意大利有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-116199933-A | Expandable microsphere with excellent temperature resistance and preparation method thereof | 快思瑞科技(上海)有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-116096764-A | Functionalized polymers | 赢创运营有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-112795169-B | Resin composition, resin film containing resin composition, prepreg, laminated board, copper-clad plate and printed circuit board | 广东生益科技股份有限公司 | 2022-07-19 | — | — | CN | claimed |
| US-10584222-B2 | Resin composition and pre-preg and laminate using the composition | SHENGYI TECHNOLOGY CO., LTD. (CN) | 2020-03-10 | — | — | US | claimed |
| WO-2020039536-A1 | A RUBBER COMPOSITION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2020-02-27 | — | — | WO | claimed |
| CN-110698715-A | Radiation crosslinking polymethacrylimide foam and preparation method thereof | 浙江中科恒泰新材料科技有限公司 | 2020-01-17 | — | — | CN | claimed |
| EP-2927281-B1 | RESIN COMPOSITION AND USE THEREOF | SHENGYI TECHNOLOGY CO LTD (CN) | 2020-01-08 | — | — | EP | claimed |
| US-10149380-B2 | Resin composition and its use | SHENGYI TECHNOLOGY CO., LTD. (CN) | 2018-12-04 | — | — | US | claimed |
| US-20180037705-A1 | RESIN COMPOSITION AND PRE-PREG AND LAMINATE USING THE COMPOSITION | SHENGYI TECHNOLOGY CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| US-20180037736-A1 | RESIN COMPOSITION AND PRE-PREG AND LAMINATE USING THE COMPOSITION | SHENGYI TECHNOLOGY CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| CN-105111354-B | Acrylonitrile-based polymethacrylimide foam and preparation method thereof | 航天材料及工艺研究所 | 2017-11-28 | — | — | CN | claimed |
| US-20150313012-A1 | RESIN COMPOSITION AND ITS USE | SHENGYI TECHNOLOGY CO., LTD. (CN) | 2015-10-29 | — | — | US | claimed |
| EP-2927281-A1 | RESIN COMPOSITION AND USE THEREOF | Shengyi Technology Co., Ltd (CN) | 2015-10-07 | — | — | EP | claimed |