Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865653 | 0.80 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL7864132 | 0.79 | CRHBP (0.32) | CRHBPCRHR2 | |
| SCHEMBL7862953 | 0.77 | CRHBP (0.33) | CRHBPCRHR2 | |
| SCHEMBL17490419 | 0.77 | MAPT (0.42) | CRHBPCRHR2CNR2 | |
| SCHEMBL7865497 | 0.76 | CCR4 (0.39) | CRHBPCRHR2 | |
| SCHEMBL7863733 | 0.74 | CRHBP (0.37) | CRHBPCRHR2 | |
| SCHEMBL2523444 | 0.73 | MBOAT4 (0.46) | CNR2 | |
| SCHEMBL2718290 | 0.72 | L3MBTL1 (0.43) | CNR2 | |
| SCHEMBL17490468 | 0.71 | MERTK (0.51) | CNR2 | |
| SCHEMBL2525732 | 0.71 | MAPT (0.41) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | NFKBIA, LITAF, CD68 | CRHBP 535/4885CRHR2 1119/4885CNR2 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.