Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.58 |
| ▸ | ITGAV | P06756 | 6/20 | 0.58 |
| ▸ | NAMPT | P43490 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856514 | 0.93 | ITGB3 (0.64) | ITGB3ITGAVNAMPTCA12CA1 | |
| SCHEMBL7863080 | 0.91 | ALDH1A1 (0.53) | ITGB3ITGAVNAMPTRAB9AMAOB | |
| SCHEMBL7856528 | 0.83 | MEN1 (0.43) | ITGB3ITGAVMAPTCA1CA2 | |
| SCHEMBL7863156 | 0.81 | EEF2K (0.41) | ITGB3ITGAVMAPTEEF2K | |
| SCHEMBL7863160 | 0.81 | EEF2K (0.41) | ITGB3ITGAVMAPTEEF2K | |
| SCHEMBL7861960 | 0.81 | THRB (0.41) | ITGB3ITGAVMAPTCA1CA2 | |
| SCHEMBL7861962 | 0.81 | THRB (0.41) | ITGB3ITGAVMAPTCA1CA2 | |
| SCHEMBL7856493 | 0.80 | NAMPT (0.53) | ITGB3ITGAVNAMPTMAPTGHSR | |
| SCHEMBL7861775 | 0.79 | EEF2K (0.43) | ITGB3ITGAVPOLBMAPTCA1 | |
| SCHEMBL7864272 | 0.79 | NAMPT (0.58) | ITGB3ITGAVNAMPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |