Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861165 | 0.79 | CCR2 (0.35) | CCR2KCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL11993144 | 0.78 | CCR2 (0.41) | CCR2KCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL998053 | 0.77 | CES2 (0.42) | SHBG | |
| SCHEMBL48662 | 0.76 | PIK3CD (0.39) | CCR2KCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL4063849 | 0.74 | KDM1A (0.33) | KCNH2SHBG | |
| SCHEMBL1701126 | 0.74 | SHBG (0.50) | SHBG | |
| SCHEMBL21164275 | 0.73 | CCR2 (0.38) | CCR2KCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL6180857 | 0.73 | SHBG (0.39) | SHBG | |
| SCHEMBL20722071 | 0.73 | PSEN1 (0.35) | KCNH2 | |
| SCHEMBL3973135 | 0.73 | PSEN1 (0.35) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |