Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777665 | 0.94 | SMN1; SMN2 (0.38) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL7571034 | 0.90 | CASP3 (0.47) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL7868304 | 0.88 | CA12 (0.34) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6815992 | 0.83 | TRPA1 (0.39) | RAB9ASMN1; SMN2LMNAPTBP1MEN1 | |
| SCHEMBL6815999 | 0.83 | TRPA1 (0.39) | RAB9ASMN1; SMN2LMNAPTBP1MEN1 | |
| SCHEMBL6811303 | 0.79 | GSK3B (0.41) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6811307 | 0.79 | GSK3B (0.41) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6816603 | 0.77 | NPC1 (0.46) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6816599 | 0.77 | NPC1 (0.46) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL7570657 | 0.76 | RAB9A (0.39) | RAB9ASMN1; SMN2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |