SCHEMBL7863923

SCHEMBL7863923

CO[C@@H]1[C@H](OC(C)(C)C)[C@@H](CO)O[C@]1(n1cnc2c(NC(=O)c3ccccc3)ncnc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.35
ADORA1 P30542 3/20 0.35
P2RY12 Q9H244 2/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6402247 0.82 ADORA1 (0.39) ADORA1P2RY12ADORA3ADORA2AADORA2B
SCHEMBL7065334 0.80 P2RY12 (0.35) PRMT6ADORA1P2RY12ADORA3ADORA2A
SCHEMBL7251215 0.78 P2RY12 (0.34) PRMT6ADORA1P2RY12ADORA3ADORA2A
SCHEMBL7251726 0.78 P2RY12 (0.33) PRMT6ADORA1P2RY12ADORA3ADORA2A
SCHEMBL7063493 0.77 P2RY12 (0.34) PRMT6ADORA1P2RY12ADORA3ADORA2A
SCHEMBL7251671 0.77 P2RY12 (0.34) PRMT6P2RY12
SCHEMBL8923627 0.73 PRMT6 (0.36) PRMT6ADORA1P2RY12
SCHEMBL29834195 0.72 ADORA1 (0.41) ADORA1
SCHEMBL28165438 0.72 ADORA1 (0.45) ADORA1ADORA3ADORA2AADORA2B
SCHEMBL7203906 0.71 ADORA1 (0.42) ADORA1ADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1108724-A2 Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules RIBOZYME PHARMACEUTICALS, INC. (US) 2001-06-20 EP disclosed