Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155286 | 0.76 | PRMT6 (0.39) | PRMT6P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL7065334 | 0.74 | P2RY12 (0.35) | PRMT6P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL7251215 | 0.73 | P2RY12 (0.34) | PRMT6P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL7251671 | 0.73 | P2RY12 (0.34) | PRMT6P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL7863923 | 0.73 | PRMT6 (0.35) | PRMT6P2RY12ADORA1 | |
| SCHEMBL7063493 | 0.72 | P2RY12 (0.34) | PRMT6P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL11040441 | 0.72 | ADORA1 (0.40) | ADORA1 | |
| SCHEMBL7251726 | 0.72 | P2RY12 (0.33) | PRMT6P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL6402247 | 0.71 | ADORA1 (0.39) | P2RY12ADORA1 | |
| SCHEMBL10481812 | 0.70 | ADORA1 (0.37) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644048-A | Process for preparing phosphorothioate oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5210264-A | S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester | ISIS PHARMACEUTICALS, INC. (US) | 1993-05-11 | — | — | US | disclosed |