SCHEMBL7864657

SCHEMBL7864657

CCC1(CC)c2cc(I)ccc2-c2ccc(C=O)cc21

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 6/20 0.33
ALDH1A1 P00352 6/20 0.33
ALDH3A1 P30838 4/20 0.33
APP P05067 1/20 0.32
TSHR P16473 1/20 0.32
ERN1 O75460 1/20 0.32
FDPS P14324 1/20 0.31
TDP2 O95551 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PTGS2 P35354 1/20 0.31
RAB9A P51151 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921820 0.85 TDP2 (0.35) TDP2
SCHEMBL12982458 0.83 PDK2 (0.38) ALDH1A3ALDH1A1ALDH3A1TSHR
SCHEMBL1085980 0.81 ALDH1A1 (0.41) ALDH1A3ALDH1A1ALDH3A1TSHRERN1
SCHEMBL25672129 0.81 ALDH1A1 (0.33) ALDH1A3ALDH1A1ALDH3A1TSHRFDPS
SCHEMBL660283 0.77 PDK2 (0.36)
SCHEMBL2781069 0.76 ALDH1A1 (0.38) ALDH1A3ALDH1A1ALDH3A1APPKDM4E
SCHEMBL12321120 0.76 PDK2 (0.35) TDP2
SCHEMBL28040153 0.76 AKR1A1 (0.36) TDP2
SCHEMBL16359287 0.75 PDK2 (0.42) ALDH1A1APPTSHRPTGS2
SCHEMBL13719008 0.75 ALDH1A1 (0.53) ALDH1A3ALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300502-B1 Multi-armed chromophores with very large two-photon absorption cross-sections THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2001-10-09 US disclosed