Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864681 | 1.00 | MEN1 (0.40) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL7863261 | 0.91 | ITGB3 (0.43) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL7863268 | 0.91 | ITGB3 (0.43) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL7861962 | 0.89 | THRB (0.41) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL7861960 | 0.89 | THRB (0.41) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL7863164 | 0.88 | MEN1 (0.43) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL7864234 | 0.84 | PGR (0.41) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL7856455 | 0.83 | PKM (0.43) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL7856452 | 0.83 | PKM (0.43) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL7856530 | 0.80 | CA1 (0.54) | MEN1KMT2ACA1CA2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |