Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | SCD | O00767 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 10/20 | 0.59 |
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tioxidazole SCHEMBL1033860 | 0.95 | LMNA (1.00) | LMNATSHRSCDRAB9ANPC1 | |
| Tioxidazole SCHEMBL23382 | 0.95 | LMNA (1.00) | LMNATSHRSCDRAB9ANPC1 | |
| Tioxidazole SCHEMBL3053813 | 0.94 | LMNA (0.98) | LMNATSHRSCDRAB9ANPC1 | |
| Tioxidazole SCHEMBL21192520 | 0.93 | LMNA (0.95) | LMNATSHRSCDRAB9ANPC1 | |
| Ciaftalan SCHEMBL16036843 | 0.82 | LMNA (0.73) | LMNATSHRSCDRAB9ANPC1 | |
| SCHEMBL544372 | 0.77 | LMNA (0.68) | LMNATSHRSCDRAB9ANPC1 | |
| SCHEMBL544557 | 0.77 | LMNA (0.68) | LMNATSHRSCDRAB9ANPC1 | |
| SCHEMBL10937620 | 0.77 | SMN1; SMN2 (0.68) | LMNATSHRSCDRAB9ANPC1 | |
| SCHEMBL16553951 | 0.77 | SCD (1.00) | LMNASCDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15271353 | 0.75 | DYRK1A (0.80) | LMNATSHRSCDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9441145-B2 | Curable material comprising silylated polymers containing urethane groups, and use thereof in sealants, adhesives, binders and/or surface modifiers | EVONIK DEGUSSA GMBH (DE) | 2016-09-13 | — | — | US | disclosed |
| US-20150159068-A1 | CURABLE MATERIAL COMPRISING SILYLATED POLYMERS CONTAINING URETHANE GROUPS, AND USE THEREOF IN SEALANTS, ADHESIVES, BINDERS AND/OR SURFACE MODIFIERS | EVONIK DEGUSSA GMBH (DE) | 2015-06-11 | — | — | US | disclosed |
| US-8993706-B2 | Curable material comprising silylated polymers containing urethane groups, and use thereof in sealants, adhesives, binders and/or surface modifiers | EVONIK DEGUSSA GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20140131928-A1 | REACTIVE LIQUID CERAMIC BINDER RESIN | EVONIK GOLDSCHMIDT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| US-8633291-B2 | Reactive liquid ceramic binder resin | EVONIK GOLDSCHMIDT GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20130267403-A1 | REACTIVE LIQUID CERAMIC BINDER | EVONIK DEGUSSA GMBH (DE) | 2013-10-10 | — | — | US | disclosed |
| US-20120068110-A1 | Hydroxyl Compounds Carrying Reactive Silyl Groups And Used As Ceramic Binders | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20110042004-A1 | CURABLE MATERIAL COMPRISING SILYLATED POLYMERS CONTAINING URETHANE GROUPS, AND USE THEREOF IN SEALANTS, ADHESIVES, BINDERS AND/OR SURFACE MODIFIERS | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| US-20100210445-A1 | REACTIVE, LIQUID CERAMIC BINDER | EVONIK DEGUSSA GMBH (DE) | 2010-08-19 | — | — | US | disclosed |
| CN-101302111-A | Reactive liquid ceramics bonding agent | GOLDSCHMIDT GMBH (DE) | 2008-11-12 | — | — | CN | disclosed |
| US-20080034794-A1 | Reactive liquid ceramic binder resin | GOLDSCHMIDT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210445-A1 | REACTIVE, LIQUID CERAMIC BINDER | CBR1, CYP2S1, TRPA1 | LMNA 1843/4885TSHR 3485/4885SCD 3068/4885 |
| US-20120068110-A1 | Hydroxyl Compounds Carrying Reactive Silyl Groups And Used As Ceramic Binders | ILK, POF1B, VCL | LMNA 1323/4885TSHR 4643/4885SCD 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.