SCHEMBL7865

SCHEMBL7865

[CH2]CS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
GAA P10253 2/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.53
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CTSK P43235 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
TLR9 Q9NR96 1/20 0.48
RECQL P46063 1/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4092360 0.82 ALDH1A1 (0.69) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL2376993 0.81 ENPP2 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL86088 0.80 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL41372 0.80 ALDH1A1 (0.82) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL63945 0.80 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL8742947 0.79 ALDH1A1 (0.72) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4391249 0.79 ALDH1A1 (0.77) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL13564611 0.78 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL10702838 0.78 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL8788972 0.78 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5184 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605310-B Synthesis method of aza five-membered ring and three-membered ring carboxylic ester derivative and salt thereof 都创(上海)医药科技股份有限公司 2024-05-07 CN claimed
US-20230390411-A1 CONJUGATE AND USE THEREOF NANJING CHEMPION BIOTECHNOLOGY CO., LTD. (CN) 2023-12-07 US claimed
EP-4285937-A1 CONJUGATE AND USE THEREOF Nanjing Chempion Biotechnology Co., Ltd. (CN) 2023-12-06 EP claimed
EP-3838890-B1 METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE NEUBORON MEDTECH LTD (CN) 2023-10-04 EP claimed
US-20230242555-A1 METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE NEUBORON MEDTECH LTD. (CN) 2023-08-03 US claimed
WO-2023138682-A1 CONJUGATE AND USE THEREOF 北京桦冠生物技术有限公司 2023-07-27 WO claimed
CN-115209922-A Conjugates and uses thereof 南京桦冠生物技术有限公司 2022-10-18 CN claimed
CN-110835310-B Intermediate, preparation method and application 南京中硼联康医疗科技有限公司 2022-09-20 CN claimed
CN-114605310-A Synthesis method of aza five-membered ring and three-membered ring carboxylate derivative and salt thereof 都创(上海)医药科技股份有限公司 2022-06-10 CN claimed
CN-110835352-B Preparation method18Process for F-BPA 南京中硼联康医疗科技有限公司 2022-05-24 CN claimed
US-4477662-A 2-Substituted thio carbapenem derivatives BEECHAM GROUP P.L.C. (GB) 1984-10-16 US claimed
US-4314059-A Process for preparing cephalosporin compounds SHIBUYA CHISEI 1982-02-02 US claimed
US-4117117-A TRIDECAPETIDE HAVING GASTRIN EFFECT MAX PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) 1978-09-26 US claimed
US-4107432-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-08-15 US claimed
US-4058661-A 7-Diacyl cephalosporins MERCK & CO., INC. (US) 1977-11-15 US claimed
US-4053286-A ACYLATION MERCK & CO., INC. (US) 1977-10-11 US claimed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US claimed
US-3985726-A DYEING AND PRINTING LEATHER, WOOL, SILK AND SYNTHETIC FIBERS CIBA-GEIGY AG (CH) 1976-10-12 US claimed
US-3953437-A Process of preparing cephalosporanic acid ester derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed