Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | BLVRB | P30043 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861833 | 0.88 | XDH (0.46) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL5407349 | 0.88 | XDH (0.54) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL5419342 | 0.86 | XDH (0.63) | XDH | |
| SCHEMBL7861879 | 0.79 | ALDH1A1 (0.56) | XDH | |
| SCHEMBL5419378 | 0.77 | XDH (0.74) | XDH | |
| SCHEMBL7854977 | 0.75 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL7860431 | 0.75 | XDH (0.54) | XDH | |
| SCHEMBL29771374 | 0.74 | XDH (0.54) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL30267879 | 0.74 | XDH (0.57) | XDH | |
| SCHEMBL8202675 | 0.74 | XDH (0.57) | XDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105708-C | 1-phenylpyrazole compounds and pharmaceutical use thereof | EFUKU CO LTD (JP) | 2003-04-16 | — | — | CN | disclosed |
| EP-0936217-B1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | WELFIDE CORP (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6015829-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| CN-1240432-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-01-05 | — | — | CN | disclosed |
| EP-0936217-A1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |