Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224538 | 0.86 | ALDH1A1 (0.55) | LOXL2TAAR1ALDH1A1MAPTLMNA | |
| SCHEMBL5566029 | 0.86 | LOXL2 (0.64) | LOXL2TAAR1ALDH1A1MAPTLMNA | |
| SCHEMBL4187565 | 0.83 | ALDH1A1 (0.62) | LOXL2TAAR1ALDH1A1MAPTLMNA | |
| SCHEMBL12461678 | 0.75 | LOXL2 (0.58) | LOXL2TAAR1ALDH1A1MAPTLMNA | |
| SCHEMBL27275491 | 0.74 | LTA4H (0.41) | MAPTLMNAMEN1KMT2ANPC1 | |
| SCHEMBL7003561 | 0.73 | KDM4E (0.49) | LOXL2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL12890327 | 0.72 | ALDH1A1 (0.54) | LOXL2TAAR1ALDH1A1MAPTLMNA | |
| SCHEMBL14133319 | 0.72 | ALDH1A1 (0.64) | LOXL2TAAR1ALDH1A1MAPTLMNA | |
| SCHEMBL7936700 | 0.71 | CYP19A1 (0.63) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL7464979 | 0.71 | ALDH1A1 (0.49) | LOXL2TAAR1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077984-A1 | 2\"-DEOXY HYGROMYCIN DERIVATIVES | Pfizer Products Inc. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999057127-A1 | 2'-DEOXY HYGROMYCIN DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-11-11 | — | — | WO | disclosed |