Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650676 | 0.77 | GABBR2 (0.50) | ALDH1A1TDP1LAP3ANPEPLMNA | |
| Phosphoric Acid SCHEMBL1882364 | 0.77 | ALDH1A1 (0.75) | ALDH1A1TDP1LAP3CYP3A4FDPS | |
| Phosphoric Acid SCHEMBL1882365 | 0.77 | ALDH1A1 (0.75) | ALDH1A1TDP1LAP3CYP3A4FDPS | |
| SCHEMBL242286 | 0.75 | ENPEP (0.50) | ALDH1A1TDP1S1PR2S1PR1S1PR3 | |
| SCHEMBL20395046 | 0.74 | LAP3 (0.39) | ALDH1A1TDP1S1PR2S1PR1S1PR3 | |
| SCHEMBL17687466 | 0.74 | S1PR2 (0.62) | S1PR2S1PR1S1PR3S1PR4LAP3 | |
| SCHEMBL6412081 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1S1PR2S1PR1S1PR3 | |
| SCHEMBL5059525 | 0.73 | S1PR1 (0.62) | ALDH1A1TDP1S1PR2S1PR1S1PR3 | |
| SCHEMBL16241036 | 0.72 | ALDH1A1 (0.68) | ALDH1A1TDP1CYP3A4 | |
| SCHEMBL30825877 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100487-A2 | COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN-ASSOCIATED MOLECULAR INTERACTIONS | Neurochem, Inc. (CA) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006133-A2 | COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN-ASSOCIATED MOLECULAR INTERACTIONS | NEUROCHEM, INC. (CA) | 2000-02-10 | — | — | WO | disclosed |