Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864040 | 0.88 | ELANE (0.43) | MAOAMAOBELANEG6PDHPGD | |
| SCHEMBL7868081 | 0.87 | MAOA (0.46) | MAOAMAOBELANEG6PDPPIA | |
| SCHEMBL7865349 | 0.83 | MAPT (0.42) | MAOAMAOBELANEG6PDHPGD | |
| SCHEMBL29700217 | 0.80 | G6PD (0.52) | MAOAMAOBG6PDHPGDMEN1 | |
| SCHEMBL638619 | 0.80 | G6PD (0.52) | MAOAMAOBG6PDHPGDMEN1 | |
| SCHEMBL1828915 | 0.74 | TP53 (0.52) | MAOAMAOBELANEHPGDMEN1 | |
| SCHEMBL29362536 | 0.74 | TP53 (0.52) | MAOAMAOBELANEHPGDMEN1 | |
| SCHEMBL31351790 | 0.74 | TRPA1 (0.52) | MAOAMAOBELANEPPIAHPGD | |
| SCHEMBL3484810 | 0.74 | TRPA1 (0.52) | MAOAMAOBELANEPPIAHPGD | |
| Potassium SCHEMBL29700401 | 0.72 | TRPA1 (0.42) | MAOAMAOBHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303562-B1 | ALKYLATING HYDROXYPHENYLBENZENESULFINIC/SULFONIC ACID COMPOUND WITH ALKENE OR SUBSTITUTED ALKENE TO FORM ALKYLATED PRODUCT | ENCHIRA BIOTECHNOLOGY CORPORATION | 2001-10-16 | — | — | US | disclosed |
| WO-2000042005-A1 | COMPOSITIONS COMPRISING 2-(2-HYDROXYPHENYL) BENZENESULFINATE AND ALKYL-SUBSTITUTED DERIVATIVES THEREOF | ENERGY BIOSYSTEMS CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |