SCHEMBL7864040

SCHEMBL7864040

Cc1ccc(-c2ccccc2S(=O)O)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.43
TRPA1 O75762 2/20 0.41
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
TP53 P04637 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HPGD P15428 2/20 0.40
ALOX15 P16050 2/20 0.40
LMNA P02545 2/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
GLA P06280 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CXCR2 P25025 1/20 0.40
MAPT P10636 3/20 0.38
USP2 O75604 2/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7865644 0.88 MAOA (0.49) ELANETRPA1MEN1KMT2ANPC1
SCHEMBL7865349 0.88 MAPT (0.42) ELANETRPA1MEN1KMT2ANPC1
SCHEMBL7868081 0.85 MAOA (0.46) ELANETRPA1MEN1KMT2ANPC1
SCHEMBL638619 0.81 G6PD (0.52) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL29700217 0.81 G6PD (0.52) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL9151925 0.79 G6PD (0.44) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL7857417 0.75 G6PD (0.41) ELANETRPA1MEN1KMT2ATP53
SCHEMBL340066 0.74 TRPA1 (0.68) TRPA1MEN1KMT2ANPC1RAB9A
SCHEMBL29819939 0.74 TRPA1 (0.68) TRPA1MEN1KMT2ANPC1RAB9A
SCHEMBL28348836 0.74 TRPA1 (0.42) TRPA1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303562-B1 ALKYLATING HYDROXYPHENYLBENZENESULFINIC/SULFONIC ACID COMPOUND WITH ALKENE OR SUBSTITUTED ALKENE TO FORM ALKYLATED PRODUCT ENCHIRA BIOTECHNOLOGY CORPORATION 2001-10-16 US disclosed
WO-2000042005-A1 COMPOSITIONS COMPRISING 2-(2-HYDROXYPHENYL) BENZENESULFINATE AND ALKYL-SUBSTITUTED DERIVATIVES THEREOF ENERGY BIOSYSTEMS CORPORATION (US) 2000-07-20 WO disclosed