Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542115 | 0.92 | ALDH1A1 (0.54) | CYP3A4CYP2C9ALOX12LMNAALDH1A1 | |
| SCHEMBL3822911 | 0.86 | ALDH1A1 (0.58) | AKR1C3LMNAF2ALDH1A1ALOX15 | |
| SCHEMBL14246822 | 0.85 | BCAT2 (0.53) | LMNAF2SLC6A3TSHRL3MBTL1 | |
| SCHEMBL28132113 | 0.85 | ALDH1A1 (0.56) | AKR1C3LMNAF2ALDH1A1ALOX15 | |
| SCHEMBL322998 | 0.84 | LMNA (0.58) | AKR1C3LMNAF2ALDH1A1ALOX15 | |
| SCHEMBL5183644 | 0.82 | ALDH1A1 (0.58) | AKR1C3LMNAF2ALDH1A1ALOX15 | |
| SCHEMBL29055923 | 0.82 | LMNA (0.56) | AKR1C3LMNAF2ALDH1A1ALOX15 | |
| SCHEMBL9956917 | 0.82 | NR4A1 (0.47) | CYP3A4CYP2C9LMNAF2ALDH1A1 | |
| SCHEMBL28345768 | 0.81 | LMNA (0.50) | CYP2C9ALOX12AKR1C3LMNAF2 | |
| SCHEMBL52413 | 0.79 | LMNA (0.70) | CYP3A4LMNAF2ALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010023276-A1 | Polymeric material, method for its manufacture, and its utilization | PREFORM RAUMGLIEDERUNGSSYSTEME GMBH (DE) | 2001-09-20 | — | — | US | claimed |
| US-20010023276-A1 | Polymeric material, method for its manufacture, and its utilization | PREFORM RAUMGLIEDERUNGSSYSTEME GMBH (DE) | 2001-09-20 | — | — | US | disclosed |