Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HAT1 | O14929 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | GLI1 | P08151 | 1/20 | 0.41 |
| ▸ | GLI2 | P10070 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695674 | 1.00 | ACACB (0.46) | ACACBPPARGPPARACNR1CNR2 | |
| Ethane SCHEMBL7865865 | 0.83 | MAOB (0.52) | ALOX5PTGS1MAOBMAOASCN9A | |
| SCHEMBL5684137 | 0.82 | MAOB (0.51) | PPARGPPARACNR2MAOBMAOA | |
| SCHEMBL5684150 | 0.82 | MAOB (0.51) | PPARGPPARACNR2MAOBMAOA | |
| SCHEMBL5684469 | 0.81 | ULK1 (0.51) | FFAR1KMT2AHAT1EP300GLI1 | |
| SCHEMBL5695724 | 0.81 | ULK1 (0.51) | FFAR1KMT2AHAT1EP300GLI1 | |
| SCHEMBL5684479 | 0.81 | ULK1 (0.51) | FFAR1KMT2AHAT1EP300GLI1 | |
| SCHEMBL5682167 | 0.80 | LTA4H (0.46) | FFAR1MAOBMAOASCN9AKMT2A | |
| Cyclopropane SCHEMBL7860821 | 0.80 | HTR2C (0.50) | PPARGPPARAMAOBMAOASCN9A | |
| SCHEMBL5697034 | 0.77 | BACE1 (0.41) | PPARGPPARACNR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303819-B1 | SODIUM CHANNEL-BLOCKING AGENT; CHRONIC OR NEUROPATHIC PAIN. | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2001-10-16 | — | — | US | disclosed |
| EP-1044186-A1 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | Newron Pharmaceuticals S.p.A. (IT) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999035123-A1 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 1999-07-15 | — | — | WO | disclosed |