SCHEMBL7865872

SCHEMBL7865872

COC(=O)c1cccc(OC)c1S(=O)(=O)Nc1nc2c(OC)cnc(OC)n2n1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
SLC40A1 Q9NP59 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.36
VDR P11473 1/20 0.36
ALDH1A1 P00352 2/20 0.35
KAT7 O95251 1/20 0.35
KAT6A Q92794 1/20 0.35
THRB P10828 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7859430 0.90 KAT7 (0.38) LMNASLC40A1POLBALDH1A1KAT7
SCHEMBL7859442 0.84 LMNA (0.41) MEN1KMT2ALMNASMN1; SMN2SLC40A1
SCHEMBL7867114 0.83 LMNA (0.40) MEN1KMT2ALMNASMN1; SMN2SLC40A1
SCHEMBL7859410 0.81 CCR4 (0.39) MEN1KMT2APOLBALDH1A1KAT7
SCHEMBL7867628 0.79 SLC40A1 (0.45) MEN1KMT2ALMNASMN1; SMN2SLC40A1
SCHEMBL6630344 0.78 CCR4 (0.37) KMT2ASLC40A1MAPT
SCHEMBL15449646 0.77 EDNRA (0.35) SMN1; SMN2
SCHEMBL7864634 0.77 SLC22A12 (0.37) MEN1KMT2AMAPK1ALDH1A1MAPT
SCHEMBL17830986 0.77 SCN9A (0.33) SMN1; SMN2THRB
SCHEMBL7864594 0.76 SLC22A12 (0.37) PTK2MAPK1ALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303814-B1 N-[1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC 2001-10-16 US disclosed
EP-0877745-B1 N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-25 EP disclosed
US-6130335-A N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-10-10 US disclosed
US-6005108-A POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS JOHNSON TIMOTHY C (US) 1999-12-21 US disclosed
US-5965490-A NOVEL COMPOUNDS WITH IMPROVED SELECTIVITY TO VALUABLE CROPS AND IMPROVED TOXICOLOGICAL AND ENVIRONMENTAL ATTRIBUTES; APPLYING TO CONTROL WEEDS BY EITHER PREEMERGENCE OR POSTEMERGENCE APPLICATION DOW AGROSCIENCES LLC (US) 1999-10-12 US disclosed