Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453024 | 0.79 | CYP3A4 (0.41) | TRPA1AAK1CYP17A1MAPTHPGD | |
| SCHEMBL7865999 | 0.70 | TRPA1 (0.43) | TRPA1AAK1LMNAHSD17B10NAMPT | |
| SCHEMBL6542475 | 0.70 | TP53 (0.42) | TRPA1AAK1LMNACYP3A4 | |
| SCHEMBL31407253 | 0.69 | TRPV1 (0.42) | TRPA1AAK1CYP17A1MAPTHSD17B10 | |
| SCHEMBL3229288 | 0.69 | NAMPT (0.47) | AAK1CYP17A1NAMPTRAB9A | |
| SCHEMBL16529436 | 0.68 | RAB9A (0.42) | MAPTCTSKRAB9ACA2CA1 | |
| SCHEMBL25216680 | 0.68 | ACE (0.47) | CYP3A4CTSK | |
| SCHEMBL25269073 | 0.68 | ACE (0.47) | CYP3A4CTSK | |
| SCHEMBL25219574 | 0.68 | ACE (0.47) | CYP3A4CTSK | |
| SCHEMBL10217082 | 0.68 | ATM (0.43) | LMNAMAPTHSD17B10CTSKCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874854-B1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS INC (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-1059293-A1 | Novel amino chlorothiazole compounds | Microcide Pharmaceuticals, Inc. (US) | 2000-12-13 | — | — | EP | disclosed |
| US-6087355-A | A THERAPEUTIC BACTERICIDE COMPOSITION FOR TREATING A METHICILLIN-RESISTANT, VANCOMYCIN-RESISTANT, OR AMPICILLIN-RESISTANT BACTERIAL INFECTION | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-07-11 | — | — | US | disclosed |
| US-6066630-A | ACTIVE AGAINST ANTIBIOTIC RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-05-23 | — | — | US | disclosed |
| US-6057312-A | TREATING ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| US-6030965-A | WIDE SPECTRAM ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-02-29 | — | — | US | disclosed |
| US-6025352-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| US-5859256-A | CHLORINATION; USEFUL AS ANTIBACTERIAL AGENTS AND IN TREATING DISEASES CAUSED BY ORGANISMS WHICH ARE RESISTANT TO BETA-LACTAM ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0874854-A2 | CEPHALOSPORIN ANTIBIOTICS | Microcide Pharmaceuticals, Inc. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997013772-A2 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-04-17 | — | — | WO | disclosed |