SCHEMBL7866352

SCHEMBL7866352

O=C(Oc1ccc(I)cc1)Oc1ccc(I)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TPMT P51580 1/20 0.44
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA9 Q16790 2/20 0.43
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RAB9A P51151 1/20 0.41
ELANE P08246 2/20 0.41
APP P05067 3/20 0.39
LMNA P02545 1/20 0.39
CA12 O43570 1/20 0.39
GSK3B P49841 1/20 0.38
TRPV1 Q8NER1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16299516 0.89 APP (0.48) MEN1KMT2AELANEAPP
SCHEMBL6937289 0.86 KMT2A (0.48) MEN1KMT2ATPMTCA1CA2
SCHEMBL13970432 0.82 GAA (0.56) MEN1KMT2ACA1CA2RAB9A
SCHEMBL7871721 0.82 TPMT (0.48) TPMTCA1CA2CA9RXRA
SCHEMBL6391243 0.81 ELANE (0.68) MEN1KMT2ACA1CA2CA9
SCHEMBL177167 0.80 LMNA (0.64) MEN1KMT2ARAB9AELANELMNA
SCHEMBL3150776 0.80 KMT2A (0.52) MEN1KMT2ATPMTCA1CA2
SCHEMBL8315899 0.80 TPMT (0.41) TPMTCA1CA2CA9RXRA
SCHEMBL18464704 0.80 EPHX2 (0.42) MEN1KMT2ATPMTCA1CA2
SCHEMBL24361156 0.78 TPMT (0.44) TPMTCA1CA2CA9RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6320016-B1 X-RAY DETECTABLE ARTICLE MOLDED FROM THERMOPLASTIC COMPOSITION; TOY, MEDICAL EQUIPMENT SUCH AS TUBES, JOINT PARTS BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 US claimed
EP-4519340-B1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING COVESTRO DEUTSCHLAND AG (DE) 2026-04-01 EP disclosed
EP-4519340-A1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING Covestro Deutschland AG (DE) 2025-03-12 EP disclosed
CN-119137182-A Method for producing polycarbonates by metal-catalyzed cross-coupling 科思创德国股份有限公司 2024-12-13 CN disclosed
WO-2023213745-A1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING COVESTRO DEUTSCHLAND AG (DE) 2023-11-09 WO disclosed
US-10597340-B2 Synthesis of fluorinated radiopharmaceuticals via electrochemical fluorination THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-03-24 US disclosed
US-20160237027-A1 HDAC8 INHIBITORS FOR TREATING CANCER HOPE CITY (US) 2016-08-18 US disclosed
US-20160137567-A1 SYNTHESIS OF FLUORINATED RADIOPHARMACEUTICALS VIA ELECTROCHEMICAL FLUORINATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-05-19 US disclosed
US-6320016-B1 X-RAY DETECTABLE ARTICLE MOLDED FROM THERMOPLASTIC COMPOSITION; TOY, MEDICAL EQUIPMENT SUCH AS TUBES, JOINT PARTS BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
US-4175544-A X-RAYS OF BODY FOR MEDICAL DIAGNOSIS Lafayette Pharmacal Inc. (US) 1979-11-27 US disclosed
US-4175544-A X-RAYS OF BODY FOR MEDICAL DIAGNOSIS Lafayette Pharmacal Inc. (US) 1979-11-27 US disclosed
US-4022814-A Iodine containing organic carbonates for use as radiographic agents LAFAYETTE PHARMACAL, INC. (US) 1977-05-10 US disclosed
US-4022814-A Iodine containing organic carbonates for use as radiographic agents LAFAYETTE PHARMACAL, INC. (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10597340-B2 Synthesis of fluorinated radiopharmaceuticals via electrochemical fluorination SLC18A2, SLC18A3, FES MEN1 369/4885KMT2A 1318/4885TPMT 2784/4885
US-20160237027-A1 HDAC8 INHIBITORS FOR TREATING CANCER HDAC8, HDAC1, HDAC7 MEN1 3778/4885KMT2A 57/4885TPMT 3988/4885
US-20160137567-A1 SYNTHESIS OF FLUORINATED RADIOPHARMACEUTICALS VIA ELECTROCHEMICAL FLUORINATION SLC18A2, SLC18A3, FES MEN1 369/4885KMT2A 1318/4885TPMT 2784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.