Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.49 |
| ▸ | CDK9 | P50750 | 19/20 | 0.49 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870752 | 0.73 | QDPR (0.42) | CCNT1CDK9QDPR | |
| SCHEMBL7868052 | 0.73 | KDM4E (0.62) | CCNT1CDK9QDPR | |
| SCHEMBL27553177 | 0.71 | QDPR (0.70) | CCNT1CDK9QDPR | |
| SCHEMBL16874849 | 0.71 | QDPR (0.66) | CCNT1CDK9QDPR | |
| Hydrochloric Acid SCHEMBL979625 | 0.70 | QDPR (0.64) | CCNT1CDK9QDPR | |
| SCHEMBL6116903 | 0.70 | TNKS (0.48) | — | |
| SCHEMBL4568259 | 0.70 | KDM4E (0.57) | — | |
| SCHEMBL5138986 | 0.69 | SIGMAR1 (0.51) | CCNT1CDK9QDPR | |
| SCHEMBL6118011 | 0.69 | KDM4E (0.54) | — | |
| SCHEMBL5019939 | 0.69 | QDPR (0.48) | CCNT1CDK9QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077213-A2 | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6046215-A | A PIPERIDINYLBENZOTHIOPHENES USEFUL FOR TRATING BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| US-5846982-A | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0812826-A1 | 1H-indole and benzo(b)thiophene derivatives with 4-(1,2,3,6-tetra:hydro:pyridinyl)- and 4-piperidinyl-groups bound to the heterocyclic ring as inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |