Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866876 | 0.84 | SLC6A4 (0.47) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL7460382 | 0.82 | PDE4A (0.44) | CASP1TSHRGAAPDE4BMEN1 | |
| SCHEMBL7866744 | 0.73 | PDE4B (0.46) | TSHRPDE4BPDE4AHTTPDE4C | |
| SCHEMBL7869820 | 0.73 | PDE4A (0.47) | PDE4BKMT2APDE4APDE4CPDE4D | |
| SCHEMBL26921463 | 0.67 | SLC6A4 (0.58) | CASP1TSHRGAAPDE4BPDE4A | |
| SCHEMBL7416563 | 0.65 | SLC6A4 (0.49) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL35210483 | 0.63 | CASP1 (0.62) | CASP1TSHRGAAMEN1KMT2A | |
| SCHEMBL7858785 | 0.63 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7858810 | 0.63 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7420776 | 0.61 | PDE4A (0.49) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | claimed |