Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815908 | 0.86 | L3MBTL1 (0.58) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8114936 | 0.86 | CYP19A1 (0.45) | ALDH1A1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL31666530 | 0.81 | CYP19A1 (0.48) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL3531728 | 0.81 | CYP19A1 (0.45) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6034041 | 0.80 | KMT2A (0.55) | ALDH1A1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL29675123 | 0.80 | FDPS (0.66) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9369968 | 0.79 | L3MBTL1 (0.52) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL1970119 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7007132 | 0.79 | MAPT (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL29619121 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |