Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 3/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862880 | 0.93 | P4HTM (0.37) | BCL2L1MCL1P4HTMBCL2FBP1 | |
| SCHEMBL7871568 | 0.91 | LIMK1 (0.41) | BCL2L1MCL1P4HTMHDAC1HDAC6 | |
| SCHEMBL7862723 | 0.88 | SMN1; SMN2 (0.44) | BCL2L1MCL1P4HTMFBP1MEN1 | |
| SCHEMBL9017993 | 0.88 | BCL2L1 (0.40) | BCL2L1MCL1P4HTMBCL2MEN1 | |
| SCHEMBL7862883 | 0.87 | KMT2A (0.41) | BCL2L1MCL1FBP1MAPTKMT2A | |
| SCHEMBL7869173 | 0.86 | RAB9A (0.44) | P4HTMMEN1LMNAMAPTALOX12 | |
| SCHEMBL9018144 | 0.86 | BCL2L1 (0.39) | BCL2L1MCL1P4HTMBCL2MEN1 | |
| SCHEMBL7871660 | 0.86 | SMN1; SMN2 (0.42) | BCL2L1MCL1P4HTMMEN1LMNA | |
| SCHEMBL7862689 | 0.85 | RAB9A (0.43) | P4HTMMEN1LMNAMAPTALOX12 | |
| SCHEMBL9574741 | 0.84 | LIMK1 (0.40) | BCL2L1MCL1P4HTMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |