Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867702 | 0.93 | BCL2L1 (0.37) | P4HTMBCL2L1BCL2FBP1MCL1 | |
| SCHEMBL7871612 | 0.91 | LIMK1 (0.41) | P4HTMALDH1A1HDAC1HDAC6NTRK2 | |
| SCHEMBL7867848 | 0.88 | SMN1; SMN2 (0.45) | P4HTMBCL2L1FBP1MCL1ALDH1A1 | |
| SCHEMBL9017993 | 0.87 | BCL2L1 (0.40) | P4HTMBCL2L1BCL2MCL1ALDH1A1 | |
| SCHEMBL8868129 | 0.87 | P4HTM (0.45) | P4HTMBCL2L1BCL2FBP1MCL1 | |
| SCHEMBL7869413 | 0.87 | SMPD1 (0.45) | FBP1HSD17B10 | |
| SCHEMBL7874547 | 0.85 | SMN1; SMN2 (0.43) | P4HTMBCL2L1MCL1HDAC6CYP2C19 | |
| SCHEMBL9018144 | 0.85 | BCL2L1 (0.39) | P4HTMBCL2L1BCL2MCL1ALDH1A1 | |
| SCHEMBL9018366 | 0.84 | P4HTM (0.37) | P4HTMBCL2L1BCL2MCL1ALDH1A1 | |
| SCHEMBL9018102 | 0.84 | BCL2L1 (0.38) | P4HTMBCL2L1BCL2MCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |