Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870566 | 0.96 | EGFR (0.43) | CA2SMPD1EGFRGABRA5P4HTM | |
| SCHEMBL7862801 | 0.92 | CA2 (0.48) | CA2L3MBTL1NAAAEGFRMGLL | |
| SCHEMBL7869413 | 0.90 | SMPD1 (0.45) | CA2SMPD1NAAAGABRA5 | |
| SCHEMBL7871556 | 0.90 | CA2 (0.47) | CA2L3MBTL1NAAAEGFRMGLL | |
| SCHEMBL7871681 | 0.89 | EGFR (0.46) | CA2EGFRGABRA5P4HTMCA12 | |
| SCHEMBL7870463 | 0.89 | KMT2A (0.46) | L3MBTL1EGFRP4HTM | |
| SCHEMBL7871651 | 0.89 | BCL2L1 (0.46) | EGFRP4HTM | |
| SCHEMBL7869442 | 0.88 | EGFR (0.43) | CA2L3MBTL1EGFRGABRA5P4HTM | |
| SCHEMBL9574879 | 0.88 | NPC1 (0.52) | CA2CA12CA1CA9CA14 | |
| SCHEMBL9018027 | 0.88 | CA2 (0.52) | CA2L3MBTL1NAAAEGFRMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |