Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018436 | 0.96 | CA2 (0.46) | CA2L3MBTL1P4HTMEGFRALDH1A1 | |
| SCHEMBL9018392 | 0.93 | CA2 (0.48) | CA2L3MBTL1NAAAP4HTMMLYCD | |
| SCHEMBL9018169 | 0.92 | CA2 (0.50) | CA2L3MBTL1NAAAP4HTMMLYCD | |
| SCHEMBL9018087 | 0.92 | CA2 (0.47) | CA2L3MBTL1NAAAP4HTMMLYCD | |
| SCHEMBL9018082 | 0.91 | CA2 (0.47) | CA2L3MBTL1NAAAP4HTMMLYCD | |
| SCHEMBL9018042 | 0.90 | SMN1; SMN2 (0.43) | CA2L3MBTL1NAAAP4HTMLMNA | |
| SCHEMBL7862801 | 0.89 | CA2 (0.48) | CA2L3MBTL1NAAAP4HTMMLYCD | |
| SCHEMBL9018404 | 0.89 | EGLN1 (0.45) | CA2P4HTMEGFRNPC1RAB9A | |
| SCHEMBL9018236 | 0.89 | HPGD (0.50) | L3MBTL1P4HTMEGFRNPC1RAB9A | |
| SCHEMBL9018337 | 0.88 | ALDH1A1 (0.45) | CA2L3MBTL1P4HTMEGFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |