Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867898 | 0.94 | KMT2A (0.50) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7870479 | 0.93 | KMT2A (0.45) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7867837 | 0.92 | NLRP3 (0.51) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL8869766 | 0.91 | P4HTM (0.53) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7867957 | 0.91 | KMT2A (0.47) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7862785 | 0.91 | LMNA (0.52) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7871643 | 0.91 | KMT2A (0.51) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7871602 | 0.89 | KMT2A (0.48) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7869464 | 0.89 | KMT2A (0.56) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL9018558 | 0.88 | ALDH1A1 (0.48) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |