Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866466 | 0.91 | TTK (0.42) | PLA2G1BATG4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL7861548 | 0.91 | HCAR3 (0.46) | KMT2AMEN1L3MBTL1KDM4EPRKAB2 | |
| SCHEMBL7868110 | 0.90 | PARP1 (0.47) | PLA2G1BATG4BMAPK1KMT2ANPC1 | |
| SCHEMBL7872872 | 0.89 | SCD (0.42) | KMT2AMEN1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7861556 | 0.88 | PLA2G1B (0.49) | PLA2G1BATG4BMAPK1KMT2ANPC1 | |
| SCHEMBL7869029 | 0.87 | SCD (0.41) | KMT2AMEN1L3MBTL1KDM4EPRKAB2 | |
| SCHEMBL8494125 | 0.86 | SCD (0.43) | KMT2AMEN1L3MBTL1KDM4EPRKAB2 | |
| SCHEMBL8495212 | 0.85 | NR0B1 (0.40) | NPC1RAB9AKDM4EPRKAB2PRKAG1 | |
| SCHEMBL7868092 | 0.85 | DGAT2 (0.38) | KMT2AMEN1L3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL7869108 | 0.84 | PRMT5 (0.46) | KMT2AMEN1L3MBTL1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |