Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137832 | 0.98 | MAPK1 (0.56) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL9343108 | 0.83 | ERCC5 (0.46) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL1516246 | 0.82 | MAPK1 (0.58) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL11305155 | 0.82 | KMT2A (0.59) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL10424361 | 0.79 | HSD11B1 (0.65) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL11145720 | 0.78 | KMT2A (0.54) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL9197870 | 0.78 | MAPK1 (0.54) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL7149069 | 0.78 | MAPK1 (0.54) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL260911 | 0.78 | ALDH1A1 (0.56) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL1699941 | 0.78 | RECQL (0.58) | MAPK1MAPTTDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326512-B1 | HYDROGENATION A B-KETOSULFONIC ACID COMPOUND | PRESIDENT OF NAGOYA UNIVERSITY (JP) | 2001-12-04 | — | — | US | disclosed |