Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868384 | 0.98 | MAPK1 (0.54) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL9343108 | 0.84 | ERCC5 (0.46) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL1516246 | 0.84 | MAPK1 (0.58) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL11305155 | 0.84 | KMT2A (0.59) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL260911 | 0.80 | ALDH1A1 (0.56) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL9197870 | 0.80 | MAPK1 (0.54) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL2188285 | 0.80 | MAPT (0.54) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL11145720 | 0.80 | KMT2A (0.54) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL1699941 | 0.80 | RECQL (0.58) | MAPK1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL7149069 | 0.80 | MAPK1 (0.54) | MAPK1MAPTTDP1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788353-B1 | CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | Clarity Pharmaceuticals Ltd (AU) | 2022-05-18 | — | — | EP | claimed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | claimed |
| EP-4387944-A1 | RADIOPHARMACEUTICALS, METHODS FOR THE PRODUCTION THEREOF, AND USES IN TREATMENT, DIAGNOSIS AND IMAGING DISEASES | Clarity Pharmaceuticals Ltd (AU) | 2024-06-26 | — | — | EP | disclosed |
| US-20240190897-A1 | NITROGEN-CONTAINING MACROCYCLIC CONJUGATES AS RADIOPHARMACEUTICALS | Clarity Pharmaceuticals Ltd (AU) | 2024-06-13 | — | — | US | disclosed |
| WO-2024098115-A1 | COMPOUNDS FOR RADIOIMAGING AND TREATMENT OF A CANCER | Clarity Pharmaceuticals Limited (AU) | 2024-05-16 | — | — | WO | disclosed |
| US-11905301-B2 | Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals | CLARITY PHARMACEUTICALS LTD. (AU) | 2024-02-20 | — | — | US | disclosed |
| WO-2024031153-A1 | DIMERIC RADIOPHARMACEUTICALS, COMPOSITIONS THEREOF AND USES THEREOF | Clarity Pharmaceuticals Limited (AU) | 2024-02-15 | — | — | WO | disclosed |
| US-20240050600-A1 | Radiopharmaceuticals, uses thereof, and methods for the production thereof | Clarity Pharmaceuticals Ltd (AU) | 2024-02-15 | — | — | US | disclosed |
| EP-4196175-A1 | RADIOPHARMACEUTICALS, USES THEREOF, AND METHODS FOR THE PRODUCTION THEREOF | Clarity Pharmaceuticals Ltd (AU) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023092184-A1 | COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF CANCER | Clarity Pharmaceuticals Ltd (AU) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023081967-A1 | COMPOUNDS AND USES THEREFOR | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-05-19 | — | — | WO | disclosed |
| WO-2001079185-A1 | NOVEL AMINO CARBOXY ALKYL DERIVATIVES OF BARBITURIC ACID | CURRY KENNETH (CA) | 2001-10-25 | — | — | WO | disclosed |
| EP-1071655-A1 | CUBANE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | Curry, Kenneth (CA) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054280-A1 | CUBANE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | CURRY KENNETH (CA) | 1999-10-28 | — | — | WO | disclosed |
| CN-1211237-A | Process for preparing 2-(thiosubstituted)-4-haloacetophenones | RHONE POULENC AGRICULTURE (GB) | 1999-03-17 | — | — | CN | disclosed |
| EP-0173748-B1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1990-01-03 | — | — | EP | disclosed |
| US-4663478-A | Process for producing a para-substituted phenol derivative | Hirai, Hidefuni | 1987-05-05 | — | — | US | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0173748-A1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4474809-A | HYPOGLYCEMIC AGENTS, ANTIDIABETIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050600-A1 | Radiopharmaceuticals, uses thereof, and methods for the production thereof | GRPR, OGFR, GHRHR | MAPK1 4461/4885MAPT 3555/4885TDP1 4662/4885 |
| US-11905301-B2 | Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals | NCL, NUDC, C3AR1 | MAPK1 4380/4885MAPT 3001/4885TDP1 3518/4885 |
| US-20240190897-A1 | NITROGEN-CONTAINING MACROCYCLIC CONJUGATES AS RADIOPHARMACEUTICALS | NCL, NUDC, C3AR1 | MAPK1 4380/4885MAPT 3001/4885TDP1 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.